DSP-6952 hydrobromide
CAS No. 1184661-33-3
DSP-6952 hydrobromide ( DSP6952;Minesapride )
产品货号. M10627 CAS No. 1184661-33-3
DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥11907 | 有现货 |
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50MG | ¥24138 | 有现货 |
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100MG | ¥32400 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称DSP-6952 hydrobromide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c.
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产品描述DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c; enhances gastric motility and causes colonic giant migrating contractions (GMCs) associated with defecation in conscious dogs, having ED50 value for inducing GMCs of 1.56mg/kg; rapidly increases fecal wet weight without increasing fluid content in mice (1-10mg/kg, p.o.).
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同义词DSP6952;Minesapride
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域——
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适应症——
化学信息
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CAS Number1184661-33-3
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分子量535.86
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分子式C21H32BrClN4O5
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(NC[C@H]1CN(CC2CCN(C(CO)=O)CC2)CCO1)C3=CC(Cl)=C(N)C=C3OC.[H]Br.[H]O[H].[H]O[H]
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化学全称(S)-4-amino-5-chloro-N-((4-((1-(2-hydroxyacetyl)piperidin-4-yl)methyl)morpholin-2-yl)methyl)-2-methoxybenzamide hydrobromide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Mine Y, et al. Eur J Pharmacol. 2018 Feb 9;826:123-132.
2. Tsubouchi T, et al. Eur J Pharmacol. 2018 Mar 1;826:96-105.
2. Tsubouchi T, et al. Eur J Pharmacol. 2018 Mar 1;826:96-105.
产品手册
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